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Lixudebart

(Synonyms: ALE.F02)
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Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis.

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  • Pureté : 98.88%
  • CAS No.: 2749515-10-2
  • Masse moléculaire:144.94 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Lixudebart
  • Experimental Validation Results for Lixudebart
  • Experimental Validation Results for Lixudebart
  • Lixudebart Chemical Structure
    Lixudebart Chemical Structure
CAS No.: 2749515-10-2
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Lixudebart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Claudin-1/CLDN1 Protein-VLP, Human can bind Lixudebart. The EC50 for this effect is 34.76 ng/mL.

  • 1/16

    Flow Cytometry analysis of PC-3 cells labelling CLDN1 (red) with Lixudebart (anti-CLDN1) (HY-P990045). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Lixudebart Chemical Structure
    1/16
  • Lixudebart
  • Immobilized Claudin-1/CLDN1 Protein-VLP, Human can bind Lixudebart. The EC50 for this effect is 34.76 ng/mL.
  • Flow Cytometry analysis of PC-3 cells labelling CLDN1 (red) with Lixudebart (anti-CLDN1) (HY-P990045). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.