MCC-134
MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent.
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- CAS No.: 181238-67-5
- Formule: C16H17N3OS
- Masse moléculaire:299.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 181238-67-5
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Masse moléculaire 299.39
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Formule C16H17N3OS
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SMILES
S=C(NC)C1(CCC1)C(C2=CC=C(C=C2)N3C=CN=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. F Kolár, et al. MCC-134, a blocker of mitochondrial and opener of sarcolemmal ATP-sensitive K+ channels, abrogates cardioprotective effects of chronic hypoxia. Physiol Res. 2005;54(4):467-71. [Content Brief]
[2]. Norihito Sasaki, et al. MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning. Circulation. 2003 Mar 4;107(8):1183-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MCC-134 Related Classifications
HY-119306 Related Classifications
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