NPC-567
NPC-567 is a bradykinin B2 receptor antagonist. NPC-567 is effective in inhibiting the acute response to allergen in the airways.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 109333-26-8
- Formule: C60H87N19O13
- Masse moléculaire:1282.45
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Bradykinin Receptor
More
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
1.4 x 10-8 M
Compound: NPC 567
|
Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells measured after 60 mins by scintillation counting method
Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells measured after 60 mins by scintillation counting method
|
[PMID: 27876250] |
| CHO | IC50 |
1.4 x 10-2 μM
Compound: NPC 567
|
Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells measured after 60 mins by scintillation counting method
Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells measured after 60 mins by scintillation counting method
|
[PMID: 27876250] |
Chemical Information
-
CAS No. 109333-26-8
-
Masse moléculaire 1282.45
-
Formule C60H87N19O13
-
Sequence
{d-Arg}-Arg-Pro-{Hyp}-Gly-Phe-Ser-{d-Phe}-Phe-Arg
-
Sequence Shortening
{d-Arg}-RP-{Hyp}-GFS-{d-Phe}-FR
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Cheronis JC, et al. A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers. J Med Chem. 1992 May 1;35(9):1563-72. [Content Brief]
[2]. Sylvin H, et al. The effect of a bradykinin B2 receptor antagonist, NPC-567, on allergen-induced airway responses in a porcine model. Inflamm Res. 2001 Sep;50(9):453-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NPC-567 Related Classifications
HY-P2118 Related Classifications
Powered by Bioz