Odorine
Odorine (Roxburghiline) is a natural product isolated from branches and leaves of Aglaia odorata. Odorine has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer.
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- CAS No.: 72755-20-5
- Formule: C18H24N2O2
- Masse moléculaire:300.40
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human A431 cells
Cytotoxicity against human A431 cells
|
[PMID: 8496701] |
| HT-1080 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 8496701] |
| KB | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 8496701] |
| KB-V1 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against vinblastine-resistant human KBV1 cells
Cytotoxicity against vinblastine-resistant human KBV1 cells
|
[PMID: 8496701] |
| KB-V1 | ED50 |
6.4 μg/mL
Compound: 3
|
Cytotoxicity against vinblastine-resistant human KBV1 cells by dose-response study in presence of 1 ug/ml vinblastine
Cytotoxicity against vinblastine-resistant human KBV1 cells by dose-response study in presence of 1 ug/ml vinblastine
|
[PMID: 8496701] |
| LNCaP | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 8496701] |
| SK-MEL-2 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
|
[PMID: 8496701] |
| ZR-75-1 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human ZR-75-1 cells
Cytotoxicity against human ZR-75-1 cells
|
[PMID: 8496701] |
Chemical Information
-
CAS No. 72755-20-5
-
Masse moléculaire 300.40
-
Formule C18H24N2O2
-
SMILES
CC[C@H](C)C(N[C@@H]1N(CCC1)C(/C=C/C2=CC=CC=C2)=O)=O
-
Synonyms
Roxburghiline
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)