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Puxitatug

(Synonyms: INT-016; AZD8205 Antibody)
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Puxitatug (INT-016; AZD8205 Antibody) is a monoclonal antibody targeting VTCN1/B7-H4. Puxitatug can be used to synthesize antibody-drug conjugates (ADCs), such as Puxitatug samrotecan (HY-171689), which can be applied to various solid tumors. Puxitatug can also be used for researching adjuvant therapies for gastric cancer.

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  • Pureté: 99.00%
  • CAS No.: 2760250-47-1
  • Masse moléculaire:145 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Puxitatug
  • Experimental Validation Results for Puxitatug
  • Experimental Validation Results for Puxitatug
  • Puxitatug Chemical Structure
    Puxitatug Chemical Structure
CAS No.: 2760250-47-1
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Puxitatug Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Puxitatug on AHC2 biosensor, can bind B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) with an affinity constant of 4.217E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Puxitatug (HY-P990059, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Puxitatug Chemical Structure
    1/16
  • Puxitatug
  • Loaded Puxitatug on AHC2 biosensor, can bind B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) with an affinity constant of 4.217E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Jurkat cells with Puxitatug (HY-P990059, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).