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Cat. No.: HY-124178

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(R)-Levrazoxane

Name: (R)-Levrazoxane
Brand: MedChemExpress
SKU: HY-124178
Price: 300.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (R)-ICRF 186)

(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases.

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CAS No.: 24613-06-7
Formule: C₁₁H₁₆N₄O₄
Masse moléculaire:268.27

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

(R)-Levrazoxane Chemical Structure

CAS No.: 24613-06-7

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Fluorescent Dye

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Description

Chemical Information

CAS No. 24613-06-7
Masse moléculaire 268.27
Formule C₁₁H₁₆N₄O₄
SMILES

C[C@H](CN(CC(N1)=O)CC1=O)N(CC(N2)=O)CC2=O
Synonyms

(R)-ICRF 186
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hasinoff BB, et al. Metabolism of the cardioprotective agents dexrazoxane (ICRF-187) and levrazoxane (ICRF-186) by the isolated hepatocyte. Xenobiotica. 1994 Oct;24(10):977-87. [Content Brief]

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