Rilopirox
Rilopirox (HOE 351) is a hydroxy-pyridone compound with antimycotic properties. Rilopirox, a chelating agent, can inhibit catalase. Rilopirox inhibits the respiratory chain. Rilopirox inhibits growth of yeast isolates with a MIC50 of 4 μg/mL. Rilopirox has the potential for vaginal candidosis and oropharyngeal Candida infections research.
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- CAS No.: 104153-37-9
- Formule: C19H16ClNO4
- Masse moléculaire:357.79
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 104153-37-9
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Masse moléculaire 357.79
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Formule C19H16ClNO4
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SMILES
O=C1C=C(C)C=C(COC2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)N1O
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Synonyms
HOE 351
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. R Kruse, et al. Studies for the elucidation of the mode of action of the antimycotic hydroxypyridone compound, rilopirox. Pharmacology. 1991;43(5):247-55. [Content Brief]
[2]. P Nenoff, et al. In vitro activity of rilopirox against fluconazole-susceptible and fluconazole-resistant Candida isolates from patients with HIV infection. Mycoses. 1999 Apr;42(1-2):55-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rilopirox Related Classifications
HY-113863 Related Classifications
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