RO5353
RO5353 is an orally active inhibitor for p53-MDM2 with an IC50 of 7 nM for MDM2. RO5353 inhibits the proliferation of wild-type p53 cancer cells with an average IC50 of 7 nM. RO5353 exhibits antitumor efficacy and good pharmacokinetic characteristics in mice.
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- CAS No.: 1360821-61-9
- Formule: C29H29Cl2FN4O4S
- Masse moléculaire:619.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 1360821-61-9
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Masse moléculaire 619.53
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Formule C29H29Cl2FN4O4S
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SMILES
NC(C1=CC(OC)=C(NC([C@H]2[C@H](C3=C(F)C(Cl)=CC=C3)[C@@]4(C(SC(Cl)=C5)=C5NC4=O)[C@H](CC(C)(C)C)N2)=O)C=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RO5353 Related Classifications
HY-12580 Related Classifications
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