S-312

S-312 is a calcium antagonist with a bicyclic dihydrothienopyridine structure. S-312 can relax the helical strips of various isolated rabbit arteries procontracted with high potassium depolarizaiton. S-312 competitively imhibits calcium-induced contractions in depolarized basilar and femoral arteries. S-312 increases AV nodal conduction time in Langenedorff-perfused isolated rabbit hearts. S-312 exhibits vasculoselectivity, particularly for cerebral vessel.

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  • CAS No.: 120004-07-1
  • Formule: C20H22N2O4S
  • Masse moléculaire:386.46
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    Please store the product under the recommended conditions in the Certificate of Analysis.

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