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Cat. No.: HY-183782

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SA1103064

SA1103064 is a potent antibiotic with antibacterial activity against multiple resistant bacterial strains. SA1103064 binds to the bacterial ribosome's nascent peptide exit tunnel. SA1103064 can be used for the research of bacterial infections.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₃₉H₅₀FN₇O₆
Masse moléculaire:731.86

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SA1103064 Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Antibiotic :

In Vitro

SA1103064 (compound 48a) binds to the E. coli ribosome's nascent peptide exit tunnel, forming π-stacking interactions with U1782-U2586 and van der Waals interactions with U2585, occupying the site of tetracenomycin X and mimicking VS1 binding contacts^[1].
SA1103064 exhibits potent antibacterial activity against multiple Gram-positive strains, including drug-resistant isolates, with MIC values ranging from 1 to 8 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

Masse moléculaire 731.86
Formule C₃₉H₅₀FN₇O₆
SMILES

[H][C@]12CCCN1C(C3=COC(C[C@@H](C[C@@H](/C=C(/C=C/CNC(/C=C/[C@H]([C@H](OC2=O)C(C)C)CCCCCN4C=C(N=N4)C5=CC=NC=C5)=O)C)O)F)=N3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Lee IJ, et al. Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome. Eur J Med Chem. 2026 May 9;316:118947. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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