108 Results for "

complement component

" in MedChemExpress (MCE) Product Catalog:
Products (108)

108 Results for "complement component" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-P7863
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
E. coli
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8
8 Cited Publications
Cat. No.: HY-P1717
CAS No.: 1427001-89-5
Synonyms: Cp40
Domaines de recherche:  

Inflammation/Immunology

AMY-101 (Cp40), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
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8
8 Cited Publications
Cat. No.: HY-P1717B
Synonyms: Cp40 acetate
Domaines de recherche:  

Inflammation/Immunology

AMY-101 acetate (Cp40 acetate), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 acetate (Cp40 acetate) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
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8
8 Cited Publications
Cat. No.: HY-P1717A
CAS No.: 1789738-04-0
Synonyms: Cp40 TFA
Domaines de recherche:  

Inflammation/Immunology

AMY-101 TFA (Cp40 TFA), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
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7
7 Cited Publications
Cat. No.: HY-P7862
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; AHUS5; complement component C3a; ASP; complement component C3b
Species:  
Human
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P7695
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P81185
Synonyms: C5; C6; C7; C8; C9; complement component 5; complement component 6; complement component 7; complement component 8; complement component 9; MAC; Membrane attack complex; TCC; Terminal complement complex.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Rat

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1
1 Cited Publications
Cat. No.: HY-P74375
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C2; complement component 2; complement C2; complement Protein; C3/C5 Convertase; ARMD14; complement component C2; CO2
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P75464
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QB; complement Subcomponent C1q Chain B; complement C1q B Chain; complement C1q Chain B; complement component 1, Q Subcomponent, Beta Polypeptide; complement component C1q, B Chain; complement component 1, Q Subcomponent, B Chain; C1QD2; complement C1q
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-P71718
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QA; complement component 1, Q Subcomponent, A Chain; complement C1q A Chain; complement C1q Chain A; complement C1q Subcomponent Subunit A; complement component C1q, A Chain; complement component 1, Q Subcomponent, Alpha Polypeptide; C1QD1
Species:  
Mouse
Source:  
P. pastoris
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1
1 Cited Publications
Cat. No.: HY-P7864
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700862
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78247
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7691
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD93; DJ737E23.1; Prev. C1QR1; ECSM3; Prev. MXRA4; Matrix-Remodeling-Associated Protein 4; C1qR(P); Matrix-Remodelling Associated 4; CDw93; C1qR; complement component 1 Q Subcomponent Receptor 1; complement component 1, Q Subcomponent, Receptor 1; Complem
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P76185
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QBP; Splicing Factor SF2-Associated Protein; Prev. HABP1; ASF/SF2-Associated Protein P32; complement component 1 Q Subcomponent-Binding Protein, Mitochondrial; Glycoprotein GC1qBP; Mitochondrial Matrix Protein P32; SF2AP32; Hyaluronan-Binding Protein 1
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P3502
CAS No.: 1841136-73-9
Synonyms: RA101495; RA3193
Target:  

Complement System

Domaines de recherche:  

Inflammation/Immunology

Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent complement component 5 (C5) inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) .
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Cat. No.: HY-NP004
Synonyms: CVF
Cobra Venom Factor (CVF) is a selective activator targeting complement components C3, C5, and factor B in the complement system. After binding to factor B, Cobra Venom Factor is cleaved by factor D, forming a stable C3/C5 convertase resistant to regulatory proteins H and I. This continuously hydrolyzes C3 and C5, depleting serum complement while inducing neutrophil migration, vascular leakage, and increased TNF-α levels. Cobra Venom Factor can be used to deplete complement and mimic complement activation-related pathological states, and is applied in animal models of complement-mediated diseases such as acute respiratory distress syndrome (ARDS), sepsis, and shock. Cobra Venom Factor can be isolated from the venom of cobras (e.g., Naja atra, Naja melanoleuca, Naja kaouthia, etc.) .
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Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103

Target:  

Complement System

Domaines de recherche:  

Inflammation/Immunology

Claseprubart (DNTH103) is an inhibitor targeting C1s of the complement system and an inhibitor of the C1 component of the complement cascade. Claseprubart is in phase 2 clinical evaluation. Claseprubart has application potential in research related to multifocal motor neuropathy and generalized myasthenia gravis .
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Cat. No.: HY-P99050
CAS No.: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009

Target:  

Complement System

Domaines de recherche:  

Endocrinology

Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome .
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Cat. No.: HY-P99358
CAS No.: 1662664-56-3
Synonyms: GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)

Target:  

Complement System

Domaines de recherche:  

Inflammation/Immunology

Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis .
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