SLCB050
SLCB050 is a compound that blocks the interaction between DX2 and p14/ARF and has anticancer activity. SLCB050 reduces the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner and induces apoptosis and senescence.
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- CAS No.: 1848971-16-3
- Formule: C21H18O6
- Masse moléculaire:366.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NSCLC | GI50 |
>50 μM
Compound: SLCB050
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Growth inhibition of human NSCLC
Growth inhibition of human NSCLC
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[PMID: 32208684] |
| SCLC | GI50 |
5 μM
Compound: SLCB050
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Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay
Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay
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[PMID: 32208684] |
Chemical Information
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CAS No. 1848971-16-3
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Masse moléculaire 366.36
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Formule C21H18O6
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SMILES
CC1(OC2=CC(OC(C=C3)=O)=C3C=C2C[C@@H]1OC(/C=C/C4=CC=CO4)=O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SLCB050 Related Classifications
HY-164536 Related Classifications
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