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Solanezumab

(Synonyms: LY-2062430)
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Solanezumab (LY-2062430) is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β (Aβ) peptide. Solanezumab binds to the mid-domain of monomeric amyloid-beta to slow brain amyloid accumulation. Solanezumab can be used for the research of Alzheimer’s disease.

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  • Pureté: ≥99.0%
  • CAS No.: 955085-14-0
  • Masse moléculaire:144.8 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Solanezumab
  • Experimental Validation Results for Solanezumab
  • Experimental Validation Results for Solanezumab
  • Solanezumab Chemical Structure
    Solanezumab Chemical Structure
CAS No.: 955085-14-0
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Solanezumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized β-Amyloid (12-28) (TFA, HY-P1051A) can bind Solanezumab. The EC50 for this effect is 1.187 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 HUVEC cells with Solanezumab (HY-P99317, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Solanezumab Chemical Structure
    1/16
  • Solanezumab
  • Immobilized β-Amyloid (12-28) (TFA, HY-P1051A) can bind Solanezumab. The EC50 for this effect is 1.187 ng/mL.
  • Flow cytometric analysis of 1.5×106 HUVEC cells with Solanezumab (HY-P99317, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.