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Cat. No.: HY-159888

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SON38

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research.

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CAS No.: 3034673-37-2
Formule: C₂₁H₂₅ClN₄O₄
Masse moléculaire:432.90

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

SON38 Chemical Structure

CAS No.: 3034673-37-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research^[1].

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]

Chemical Information

CAS No. 3034673-37-2
Masse moléculaire 432.90
Formule C₂₁H₂₅ClN₄O₄
SMILES

ClC1=CC([N+]([O-])=O)=C(C=C1)OCC(NCCN2CCN(CC2)CC3=CC=CC=C3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Leuci R, et al. Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates[J]. Bioorganic Chemistry, 2024, 153: 107895. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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SON38

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SON38 Related Classifications

HY-159888 Related Classifications