Copy Link Print Information

Vibecotamab

(Synonyms: XmAb14045)
Avis client

Based on 1 Customer Validation

Vibecotamab (XmAb14045) is a potent bispecific antibody targeting both CD123 and CD3. Vibecotamab targets T cell-mediated killing of CD123-expressing cells, regardless of T cell antigen specificity. Vibecotamab is a full length immunoglobulin molecule. Vibecotamab can be studied in research for diseases such as Myelodysplastic syndrome and acute myeloid leukemia. Recommend Isotype Control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté: 99.34%
  • CAS No.: 2138442-13-2
  • Masse moléculaire:126.15 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vibecotamab
  • Experimental Validation Results for Vibecotamab
  • Experimental Validation Results for Vibecotamab
  • Experimental Validation Results for Vibecotamab
  • Vibecotamab Chemical Structure
    Vibecotamab Chemical Structure
CAS No.: 2138442-13-2
Size
Prix
Stock
Quantité
Amount: USD 0.00
Please select quantity
or
or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Vibecotamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
  • Activité biologique
  • Chemical Information
  • Pureté et documentation
  • Références
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Obtenir un devis En stock

Other size
Obtenir un devis
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Enregistrer
Sign in to MedChemExpress
Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3

  • 1/16

    Immobilized Vibecotamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 0.48 ng/mL.

  • 1/16

    Immobilized Vibecotamab can bind Human IL-3R alpha/CD123 Protein (ECD, His Tag). The EC50 for this effect is 7.66 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Vibecotamab (HY-P99521). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Vibecotamab Chemical Structure
    1/16
  • Vibecotamab
  • Immobilized Vibecotamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 0.48 ng/mL.
  • Immobilized Vibecotamab can bind Human IL-3R alpha/CD123 Protein (ECD, His Tag). The EC50 for this effect is 7.66 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Vibecotamab (HY-P99521). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3