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Cat. No.: HY-149593

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VU0506013

Name: VU0506013
Brand: MedChemExpress
SKU: HY-149593
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VU0506013 is a selective positive allosteric modulator of Y4R (K_B = 34.9 nM). VU0506013 can be used in the development of anti-obesity agents targeting Y4R.

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CAS No.: 1207036-87-0

Formule: C₂₀H₂₃N₃O₄

Masse moléculaire:369.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

VU0506013 Chemical Structure

CAS No.: 1207036-87-0

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Data Download

Data Sheet (267 KB)

Instruction de manipulation (2659 KB)

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Voir tous les produits spécifiques à Isoform Neuropeptide Y Receptor
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NPY Y₁ receptor

NPY Y₂ receptor

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Activité biologique

Description

VU0506013 is a selective positive allosteric modulator of Y4R (K_B = 34.9 nM). VU0506013 can be used in the development of anti-obesity agents targeting Y4R^[1].

IC₅₀ & Target
^[1]

NPY Y₄ receptor

Voir tous les produits spécifiques à Isoform Neuropeptide Y Receptor :

NPY Y₁ receptor

NPY Y₂ receptor

NPY Y₄ receptor

NPY Y₅ receptor

Chemical Information

CAS No. 1207036-87-0

Masse moléculaire 369.41

Formule C₂₀H₂₃N₃O₄

SMILES

O=C(N1CCCC1)C(C=C2NC(COC3=C(C)C=CC=C3)=O)=CN(C)C2=O

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Schüß C, et al. Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013. J Med Chem. 2023 Jul 13;66(13):8745-8766. [Content Brief]

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Volume Volume

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

×

Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

VU0506013 Related Classifications

HY-149593 Related Classifications

GPCR/G Protein Neuronal Signaling

Neuropeptide Y Receptor

Aires thérapeutique

Metabolic or Endocrine Disease

Metabolic Disease

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Keywords

VU0506013
1207036-87-0
VU 0506013
VU-0506013
Neuropeptide Y Receptor
obesity
Inhibitor
inhibitor
inhibit

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Nom du produit:
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MCE Japan Authorized Agent:

VU0506013

Voir tous les produits spécifiques à Isoform Neuropeptide Y Receptor

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

VU0506013 Related Classifications

HY-149593 Related Classifications

Bioz

Keywords

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