ZN148
Based on 1 Customer Validation
ZN148 is a zinc-chelating synthetic metallo-β-lactamase (MBL) inhibitor which attenuates MBL-mediated carbapenem resistance. ZN148 can restore the in vitro clinical susceptibility to carbapenems in >98% of a large international collection of MBL-producing clinical Enterobacterales strains. ZN148 can be utilized in research on anti MBL-producing bacteria.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2190527-04-7
- Formule: C26H33N5O6
- Masse moléculaire:511.57
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: S29
|
Cytotoxicity against human HepG2 cells incubated for 24 hrs by AlamarBlue-based assay
Cytotoxicity against human HepG2 cells incubated for 24 hrs by AlamarBlue-based assay
|
[PMID: 37360393] |
Chemical Information
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CAS No. 2190527-04-7
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Appearance Solid
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Masse moléculaire 511.57
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Formule C26H33N5O6
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Color White to yellow
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SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CN(C)C(C(C=N1)=CC=C1CN(CC2=CC=CC=N2)CC3=CC=CC=N3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)