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Cat. No.: HY-186107

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ZY36

ZY36 is a SaClpP agonist with an EC₅₀ of 1.01 μM against Staphylococcus aureus. ZY36 activates SaClpP-mediated proteolysis. ZY36 inhibits the growth of Staphylococcus aureus. ZY36 is applicable to studies related to Staphylococcus aureus infections, such as peritonitis.

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Formule: C₂₇H₃₂F₄N₄O₃
Masse moléculaire:536.56

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ZY36 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

ZY36 activates purified S. aureus ClpP-mediated α-casein hydrolysis with an EC₅₀ of 1.01 ± 0.2 μM^[1].
ZY36 inhibits the growth of S. aureus Newman with an MIC of 0.5 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 536.56
Formule C₂₇H₃₂F₄N₄O₃
SMILES

O=C(N(CCC1=O)[C@@]([H])(CN2CC3=C4C=CC=CC4=C(F)C=C3)N1[C@@H]([C@@H](C)CC)C2=O)NCCCC(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Zhang T, et al. Structure-Guided Development of ClpP Agonists with Potent Therapeutic Activities against Staphylococcus aureus Infection. J Med Chem. 2025 Jan 23;68(2):1810-1823. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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