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製品番号: HY-N10286

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Chetoseminudin B

Chetoseminudin B possesses mushroom tyrosinase inhibitory activity with IC₅₀ of 31.7 μM.

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CAS 番号: 658711-87-6
分子式: C₁₇H₂₁N₃O₃S₂
分子量:379.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Chetoseminudin B 構造式

CAS 番号: 658711-87-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
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生物活性

製品説明

Chetoseminudin B possesses mushroom tyrosinase inhibitory activity with IC₅₀ of 31.7 μM^[1].

IC₅₀ & Target

IC₅₀: 31.7 μM (mushroom tyrosinase)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 6	Cytotoxicity against human HepG2 cells by SRB method Cytotoxicity against human HepG2 cells by SRB method	[PMID: 23079524]
Jurkat	IC₅₀	94.9 μM Compound: 8	Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay	[PMID: 20303767]
Lymphocyte	IC₅₀	24 μM Compound: 8	Immunosuppression of mouse spleen lymphocytes Immunosuppression of mouse spleen lymphocytes	[PMID: 20303767]
MCF7	IC₅₀	>100 μM Compound: 6	Cytotoxicity against human MCF7 cells by SRB method Cytotoxicity against human MCF7 cells by SRB method	[PMID: 23079524]
NCI-H460	IC₅₀	>100 μM Compound: 6	Cytotoxicity against human NCI-H460 cells by SRB method Cytotoxicity against human NCI-H460 cells by SRB method	[PMID: 23079524]
SF-268	IC₅₀	>100 μM Compound: 6	Cytotoxicity against human SF268 cells by SRB method Cytotoxicity against human SF268 cells by SRB method	[PMID: 23079524]
T-cell	IC₅₀	24 μg/mL Compound: 3, CS-C	Immunosuppressive activity in BALB/c mouse splenic T lymphocytes assessed as inhibition of Con A-induced cell proliferation after 72 hrs by MTT assay Immunosuppressive activity in BALB/c mouse splenic T lymphocytes assessed as inhibition of Con A-induced cell proliferation after 72 hrs by MTT assay	[PMID: 14738397]

化学情報

CAS 番号 658711-87-6
分子量 379.50
分子式 C₁₇H₂₁N₃O₃S₂
SMILES

CS[C@]1(C(N([C@@](SC)(C(N1)=O)CO)C)=O)CC2=CNC3=CC=CC=C23
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
- Microorganisms
Phaeosphaeria fuckelii
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zhai YJ, et al. Phaeosphaones: Tyrosinase Inhibitory Thiodiketopiperazines from an Endophytic Phaeosphaeria fuckelii. J Nat Prod. 2020;83(5):1592-1597. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=

濃度濃度

×

体積体積

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

×

体積 _(開始) 体積 _(開始)

=

濃度 _(終了) 濃度 _(終了)

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体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献