Chondrocurine
Chondrocurine (Tubocurine) is an alkaloid found in the roots of Cissampelos pareira Linn. Chondrocurine is an acetylcholinesterase (AChE) inhibitor with an IC50 of 7.46 μM.
For research use only. We do not sell to patients.
- CAS No.: 477-58-7
- Formula: C36H38N2O6
- Molecular Weight:594.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE 7.46 μM (IC50) |
In Vitro
Chondrocurine (Compound 9) potently inhibits acetylcholinesterase with an IC50 of 7.46 ± 0.19 μM[1].
Chondrocurine (48 h) is inactive against HeLa, HT29, and MCF-7 human cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 477-58-7
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Molecular Weight 594.70
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Formula C36H38N2O6
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SMILES
CN1CCC2=C(C3=C(O)C(OC)=C2)[C@]1(CC4=CC=C(O)C(OC5=C(OC)C=C(CCN(C)[C@]6(CC7=CC=C(O3)C=C7)[H])C6=C5)=C4)[H]
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Synonyms
Tubocurine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chondrocurine Related Classifications
HY-165281 Related Classifications
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