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Cat. No.: HY-182490

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Chrodrimanin H

Chrodrimanin H (Compound 13) is a sesquiterpenoid compound. Chrodrimanin H is isolated from the fungus Talaromyces primulinus H21. Chrodrimanin H blocks lipopolysaccharide-induced NO production in immune cells with an IC50 of 24.71 μM.

For research use only. We do not sell to patients.

CAS No.: 1446801-59-7
Formula: C₂₅H₃₂O₆
Molecular Weight:428.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chrodrimanin H Chemical Structure

CAS No.: 1446801-59-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Fungal Metabolite

All Endogenous Metabolite Isoforms :

All NO Synthase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	50 μM Compound: 7	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 26046820]

In Vitro

Chrodrimanin H (Compound 13) (50 μM; 48 h for viability) inhibits nitric oxide production in LPS-induced RAW 264.7 cells with an IC₅₀ of 24.71 μM, and exhibits low cytotoxicity at a concentration of 50 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1446801-59-7
Molecular Weight 428.52
Formula C₂₅H₃₂O₆
SMILES

C[C@@]12[C@@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H](C5)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Microorganisms
endophytic fungus Talaromyces primulinus H21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chen JQ, et al. Talaesthanes A-C, three new meroterpenoids from the endophytic fungus Talaromyces primulinus H21. Fitoterapia. 2024;177:106085. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Chrodrimanin H

All Endogenous Metabolite Isoforms

All NO Synthase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Chrodrimanin H Related Classifications

HY-182490 Related Classifications