Chrodrimanin H
Chrodrimanin H (Compound 13) is a sesquiterpenoid compound. Chrodrimanin H is isolated from the fungus Talaromyces primulinus H21. Chrodrimanin H blocks lipopolysaccharide-induced NO production in immune cells with an IC50 of 24.71 μM.
For research use only. We do not sell to patients.
- CAS No.: 1446801-59-7
- Formula: C25H32O6
- Molecular Weight:428.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
Fungal Metabolite |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
50 μM
Compound: 7
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Cytotoxicity against human A549 cells by sulforhodamine B assay
Cytotoxicity against human A549 cells by sulforhodamine B assay
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[PMID: 26046820] |
In Vitro
Chrodrimanin H (Compound 13) (50 μM; 48 h for viability) inhibits nitric oxide production in LPS-induced RAW 264.7 cells with an IC50 of 24.71 μM, and exhibits low cytotoxicity at a concentration of 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1446801-59-7
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Molecular Weight 428.52
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Formula C25H32O6
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SMILES
C[C@@]12[C@@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H](C5)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
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Structure Classification
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Initial Source
endophytic fungus Talaromyces primulinus H21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chrodrimanin H Related Classifications
HY-182490 Related Classifications
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