2. Anti-infection Metabolic Enzyme/Protease Immunology/Inflammation
  3. Fungal Endogenous Metabolite NO Synthase
  4. Chrodrimanin H

Chrodrimanin H (Compound 13) is a sesquiterpenoid compound. Chrodrimanin H is isolated from the fungus Talaromyces primulinus H21. Chrodrimanin H blocks lipopolysaccharide-induced NO production in immune cells with an IC50 of 24.71 μM.

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Chrodrimanin H

Chrodrimanin H Chemical Structure

CAS No. : 1446801-59-7

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Chrodrimanin H Related Antibodies

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Description

Chrodrimanin H (Compound 13) is a sesquiterpenoid compound. Chrodrimanin H is isolated from the fungus Talaromyces primulinus H21. Chrodrimanin H blocks lipopolysaccharide-induced NO production in immune cells with an IC50 of 24.71 μM[1].

IC50 & Target[1]

Fungal Metabolite

 

In Vitro

Chrodrimanin H (Compound 13) (50 μM; 48 h for viability) inhibits nitric oxide production in LPS-induced RAW 264.7 cells with an IC50 of 24.71 μM, and exhibits low cytotoxicity at a concentration of 50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chrodrimanin H Related Antibodies
Molecular Weight

428.52

Formula

C25H32O6
CAS No.
SMILES

C[C@@]12[C@@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H](C5)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
Structure Classification
Initial Source

endophytic fungus Talaromyces primulinus H21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Chrodrimanin H Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chrodrimanin H1446801-59-7FungalEndogenous MetaboliteNO SynthaseNitric oxide synthasesNOSnitric oxidelipopolysaccharideTalaromyces primulinus H21RAW 264.7 cellsimmune cellsendophytic fungusInhibitorinhibitorinhibit

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