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Clodronate liposomes

9 Cited Publications
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Based on 9 publication(s) in Google Scholar

Clodronate liposomes, a mixture of Clodronate encapsulated by phospholipids, is a macrophage scavenger. Clodronate liposomes is engulfed by macrophages in the body. Under the action of lysosomal phosphatases in macrophages, Clodronate dissolved in liposomes will be gradually released and accumulated in cells. When a certain concentration is reached, macrophages will be irreversibly damaged and apoptosis will be induced.

For research use only. We do not sell to patients.

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    Store at 4°C, do not freeze

  • Clodronate liposomes Chemical Structure
  • Experimental Validation Results for Clodronate liposomes
  • Experimental Validation Results for Clodronate liposomes
  • Experimental Validation Results for Clodronate liposomes
  • Clodronate liposomes Chemical Structure
    Clodronate liposomes Chemical Structure
  • Experimental Validation Results for Clodronate liposomes
  • Experimental Validation Results for Clodronate liposomes
  • Experimental Validation Results for Clodronate liposomes
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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IFIn Vivo Efficacy StudyHistological Imaging/Staining
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  • In Vivo Efficacy Study
  • Histological Imaging/Staining
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  • Clodronate liposomes Chemical Structure
    Clodronate liposomes Chemical Structure
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    Clodronate liposomes purchased from MedChemExpress. Usage Cited in: Cell Oncol (Dordr). 2026 Mar 23;49(2):61. [Abstract]

    Customer Validation
     Verification of macrophage deletion by Clodronate liposomes. Clodronate liposomes (40 mg/kg; i.p.) were administered twice weekly for two weeks before tumor inoculation and then weekly for four additional weeks. IF analysis of F4/80+ macrophages in the following groups: PBS-liposomes, ADM, Clodronateliposome, or ADM + Clodronate-liposome. Scale bar, 50 μm.

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    Clodronate liposomes purchased from MedChemExpress. Usage Cited in: FASEB J. 2025 Aug 15;39(15):e70923. [Abstract]

    Customer Validation
     Representative micro‐CT images showing new bone formation in each group. Both the YAP1 inhibitor group and the Clodronate liposomes group exhibited impaired bone regeneration compared to the Ctrl group.

  • 1/16

    Clodronate liposomes purchased from MedChemExpress. Usage Cited in: FASEB J. 2025 Aug 15;39(15):e70923. [Abstract]

    Customer Validation
     H&E staining and Masson's trichrome staining showed dense lamellar bone formation in the Ctrl group, while the YAP1 inhibitor and Clodronate liposomes groups exhibited sparse trabeculae, fibrous tissue infiltration, or immature callus.

  • Clodronate liposomes