CLP257 (Standard)
CLP257 (Standard) is the analytical standard of CLP257 (HY-110143). This product is intended for research and analytical applications. CLP257 is a selective K+-Cl cotransporter KCC2 activator with an EC50 of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally.
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- CAS. Nr.: 1181081-71-9
- Formel: C14H14FN3O2S
- Molecular Weight:307.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
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Help & FAQs
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 1181081-71-9
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Molecular Weight 307.34
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Formel C14H14FN3O2S
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SMILES
O=C1N=C(N2CCCCN2)S/C1=C\C3=CC=C(F)C=C3O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CLP257 (Standard) Related Classifications
HY-110143R Related Classifications
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