Cochliomycin A
Cochliomycin A ((+)-Cochliomycin A) can be isolated from Gorgonian-Derived Fungus Cochliobolus lunatus. Cochliomycin A has antifouling activity (EC50: 1.2 μg/mL). Cochliomycin A inhibits barnacle larval settlement by stimulating the NO/cGMP pathway. Cochliomycin A also has moderate antibacterial activity against S. aureus.
For research use only. We do not sell to patients.
- CAS No.: 1278520-07-2
- Formula: C22H28O7
- Molecular Weight:404.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1278520-07-2
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Molecular Weight 404.45
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Formula C22H28O7
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SMILES
OC1=C(C(O[C@H](C/C=C/[C@@](O2)([H])[C@@]3([H])OC2(C)C)C)=O)C(/C=C/C[C@@H]3O)=CC(OC)=C1
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Synonyms
(+)-Cochliomycin A
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Structure Classification
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Initial Source
Cochliobolus lunatus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Shao CL, et al. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod. 2011 Apr 25;74(4):629-33. [Content Brief]
[2]. Wang KL, et al. Cochliomycin A inhibits the larval settlement of Amphibalanus amphitrite by activating the NO/cGMP pathway. Biofouling. 2016;32(1):35-44. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)