CPTH6 hydrobromide

Cat. No.: HY-115406A Purity: 98.02%: Data Sheet
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CPTH6 hydrobromide is a thiazole derivative which activates apoptotic program and increases autophagic features in human acute myeloid leukemia cell lines. CPTH6 can be used for cancer research.

For research use only. We do not sell to patients.

CPTH6 hydrobromide Chemical Structure

CAS No. : 2321332-57-2

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Purity & Documentation
References
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Description

CPTH6 hydrobromide is a thiazole derivative which activates apoptotic program and increases autophagic features in human acute myeloid leukemia cell lines. CPTH6 can be used for cancer research^[1].

In Vitro

CPTH6 (50, 100 μM, 6-72 h) induces autophagic markers time and does-dependently in several cancer cell lines^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

386.74

Formula

C₁₅H₁₇BrClN₃S

CAS No.

2321332-57-2

Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(C2=CSC(N/N=C3CCC(C/3)C)=N2)C=C1.Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 66.67 mg/mL (172.39 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5857 mL	12.9286 mL	25.8572 mL
5 mM	0.5171 mL	2.5857 mL	5.1714 mL
10 mM	0.2586 mL	1.2929 mL	2.5857 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

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Data Sheet (269 KB) SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Ragazzoni Y, et al. The thiazole derivative CPTH6 impairs autophagy. Cell Death Dis. 2013 Mar 7;4(3):e524. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5857 mL	12.9286 mL	25.8572 mL	64.6429 mL
	5 mM	0.5171 mL	2.5857 mL	5.1714 mL	12.9286 mL
	10 mM	0.2586 mL	1.2929 mL	2.5857 mL	6.4643 mL
	15 mM	0.1724 mL	0.8619 mL	1.7238 mL	4.3095 mL
	20 mM	0.1293 mL	0.6464 mL	1.2929 mL	3.2321 mL
	25 mM	0.1034 mL	0.5171 mL	1.0343 mL	2.5857 mL
	30 mM	0.0862 mL	0.4310 mL	0.8619 mL	2.1548 mL
	40 mM	0.0646 mL	0.3232 mL	0.6464 mL	1.6161 mL
	50 mM	0.0517 mL	0.2586 mL	0.5171 mL	1.2929 mL
	60 mM	0.0431 mL	0.2155 mL	0.4310 mL	1.0774 mL
	80 mM	0.0323 mL	0.1616 mL	0.3232 mL	0.8080 mL
	100 mM	0.0259 mL	0.1293 mL	0.2586 mL	0.6464 mL