1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. CRA-2059

CRA-2059 

Cat. No.: HY-19303
Handling Instructions

CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ).

For research use only. We do not sell to patients.

CRA-2059 Chemical Structure

CRA-2059 Chemical Structure

CAS No. : 256649-36-2

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Description

CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].

In Vitro

Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1].

Molecular Weight

750.80

Formula

C₃₄H₄₆N₁₂O₈

CAS No.

256649-36-2

SMILES

NC(NC1=CC=C(CNC(N2CCN(C(O[[email protected]@H]3COC4[[email protected]](OC(N5CCN(C(NCC6=CC=C(NC(N)=N)C=C6)=O)CC5)=O)COC34)=O)CC2)=O)C=C1)=N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CRA-2059CRA2059CRA 2059Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesproteaseHTbetainteractionpsoriasisulcerativecolitisInhibitorinhibitorinhibit

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CRA-2059
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