(R,R,R)-AHPC hydrochloride
(R,R,R)-AHPC hydrochloride is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (R,R,R)-AHPC hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- Formula: C22H31ClN4O3S
- Molecular Weight:467.02
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
VHL |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 467.02
-
Formula C22H31ClN4O3S
-
SMILES
N[C@H](C(C)(C)C)C(N1[C@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)