1. PROTAC
  2. Ligands for E3 Ligase
  3. (R,R,R)-AHPC hydrochloride

(R,R,R)-AHPC hydrochloride is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (R,R,R)-AHPC hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.

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(R,R,R)-AHPC hydrochloride

(R,R,R)-AHPC hydrochloride Estructura química

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Descripciòn

(R,R,R)-AHPC hydrochloride is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (R,R,R)-AHPC hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.

IC50 & Target

VHL

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

467.02

Fòrmula

C22H31ClN4O3S

SMILES

N[C@H](C(C)(C)C)C(N1[C@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O.Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación
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(R,R,R)-AHPC hydrochloride Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
(R,R,R)-AHPC hydrochloride
Cat. No.:
HY-W998245
Cantidad:
MCE Japan Authorized Agent: