Crobenetine hydrochloride

(Synonyms: BIII-890 hydrochloride; BIII-890 CL)

Crobenetine hydrochloride (BIII-890 hydrochloride) is the hydrochloride form of Crobenetine (HY-16923). Crobenetine hydrochloride is a selective inhibitor for Na+ channel. Crobenetine hydrochloride displaces 3HBTX from site 2 of the Na+ channel (IC50=49 nM) in rat brain synaptosomes, exhibits only low binding affinity for other receptors and ion channels. Crobenetine hydrochloride protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents.

For research use only. We do not sell to patients.

The Crobenetine hydrochloride was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

  • CAS No.: 221018-88-8
  • Formula: C25H34ClNO2
  • Molecular Weight:416.00
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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