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Cat. No.: HY-137566

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Cucumarioside H

Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

For research use only. We do not sell to patients.

CAS No.: 116524-58-4
Formula: C₆₀H₉₂O₂₉S
Molecular Weight:1309.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Cucumarioside H Chemical Structure

CAS No.: 116524-58-4

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Description

Chemical Information

CAS No. 116524-58-4
Molecular Weight 1309.42
Formula C₆₀H₉₂O₂₉S
SMILES

O[C@H]1[C@H](O[C@H]([C@H]([C@H]1O[C@H]2[C@H]([C@H]([C@H](CO2)O)OC)O)O)O[C@@H]3[C@@H](O[C@@H]([C@@H]([C@@H]3O)O[C@@H]4OC[C@@H]([C@@H]([C@@H]4O)O)O)O[C@@H]5[C@@H](OC[C@@H](OS(O)(=O)=O)[C@@H]5O)O[C@@H]6CC[C@@]7([C@@H]8CC[C@@]9%10[C@@](C[C@@H](OC(C)=O)[C@@H]9[C@@](/C=C/C=C(C)/C)(OC%10=O)C)(C8=CC[C@@H]7C6(C)C)C)C)C)CO
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Animals
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Structures and cytotoxic properties of cucumariosides H2, H3 and H4 from the sea cucumber Eupentacta fraudatrix

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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