1. PROTAC
  2. PROTAC Linker
  3. Cy5-PEG6-NHS ester

Cy5-PEG6-NHS ester 

Cat. No.: HY-141044
Handling Instructions

Cy5-PEG6-NHS ester (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Cy5-PEG6-NHS ester Chemical Structure

Cy5-PEG6-NHS ester Chemical Structure

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Description

Cy5-PEG6-NHS ester (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

951.58

Formula

C₅₁H₇₁ClN₄O₁₁

SMILES

CC1(C)C2=C(C=CC=C2)[N+](CCCCCC(NCCOCCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O)=C1/C=C/C=C/C=C4C(C)(C)C(C=CC=C5)=C5N\4C.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

Cy5-PEG6-NHS esterPROTAC LinkerInhibitorinhibitorinhibit

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Product name:
Cy5-PEG6-NHS ester
Cat. No.:
HY-141044
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