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D359-0396

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D359-0396 is an orally active NLRP3 inflammasome inhibitor. D359-0396 inhibits pyroptosis and IL-1β release in macrophages. D359-0396 also inhibits the oligomerization of NLRP3, ASC and the cleavage of GSDMD. D359-0396 alleviates EAE, and also improves survival after septic shock in mice.

For research use only. We do not sell to patients.

  • Purity: 99.98%
  • CAS No.: 1031977-31-7
  • Formula: C24H24N4O2
  • Molecular Weight:400.47
  • Storage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • D359-0396 Chemical Structure
    D359-0396 Chemical Structure
CAS No.: 1031977-31-7
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All NOD-like Receptor (NLR) Isoforms

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100 mg

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  • D359-0396 Chemical Structure
    D359-0396 Chemical Structure
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  • D359-0396