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Art. -Nr.: HY-151960

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Antitubercular agent-36

Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of Mtb_H37Rv with a MIC₉₀ value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2883173-82-6
Formel: C₁₈H₁₇N₃O₃
Molecular Weight:323.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Antitubercular agent-36 Chemical Structure

CAS. Nr.: 2883173-82-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
THP-1	IC₅₀	>100 μg/mL Compound: 53	Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 36399878]

In Vitro

Antitubercular agent-36 (0-20 μg/mL; 3-4 d) shows inhibitory effect to Mtb_H37Rv with a MIC₉₀ value of 1.25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2883173-82-6
Molecular Weight 323.35
Formel C₁₈H₁₇N₃O₃
SMILES

CCOC(C1=NOC(C2=NC(NC3=CC=C(C=C3)C)=CC=C2)=C1)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Girardini M, et al. Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114916. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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