HW161023
HW161023 (compound 5) is an orally active AP2-associated protein kinase 1 (AAK1) inhibitor with IC50 values of 5.4 nM and 11.9 μM aganist of AAK1and hERG, respectively. HW161023 inhibits the pain in chronic constriction injury of the sciatic nerve rat model.
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- CAS. Nr.: 2920698-73-1
- Formel: C20H24F2N4O
- Molecular Weight:374.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 2920698-73-1
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Molecular Weight 374.43
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Formel C20H24F2N4O
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SMILES
CC(C)C[C@](C)(N)COC1=CC=C(C2=CC=NC(C(F)F)=C2)C3=NC=CN13
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)