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Art. -Nr.: HY-106951

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MK 386

(Synonyms: L-733692)

MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition.

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CAS. Nr.: 158493-17-5
Formel: C₂₈H₄₉NO
Molecular Weight:415.69

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

MK 386 Chemical Structure

CAS. Nr.: 158493-17-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
- In Vitro
Chemical Information
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Biologische Aktivität

Beschreibung

MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition^[1].

IC₅₀ & Target

5-α-reductase I^[1]

In Vitro

MK 386 (5 μM; 48 h) modulates the mRNA level of related genes, in LNCaP cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 158493-17-5
Molecular Weight 415.69
Formel C₂₈H₄₉NO
SMILES

C[C@@]12[C@]3([H])[C@]([C@@H](C)C[C@@]1([H])N(C(CC2)=O)C)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3
Synonyms

L-733692
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
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- IC₅₀ & Target
- In Vitro
Chemical Information
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MK 386

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Stigmasterol glucoside

Dutasteride

12-O-Methylcarnosic acid

Epristeride (Standard)

Alpha-Estradiol-d2

Finasteride (Standard)

12-O-Methylcarnosic acid (Standard)

Finasteride acetate

CGP-53153

Dutasteride (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

MK 386

Epristeride

Finasteride

Stigmasterol glucoside

Dutasteride

12-O-Methylcarnosic acid

Epristeride (Standard)

Alpha-Estradiol-d2

Finasteride (Standard)

12-O-Methylcarnosic acid (Standard)

Finasteride acetate

CGP-53153

Dutasteride (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

MK 386 Related Classifications

HY-106951 Related Classifications

Bioz