SAS-0132

SAS-0132 is a selective Sigma 2 receptor (Sig2R) antagonist (Ki: 90 nM) that can cross the blood-brain barrier. SAS-0132 is capable of regulating intracellular Ca2+ levels and modulating PGRMC1-related pathways. SAS-0132 exhibits neuroprotective activity and can improve cognitive impairment in Alzheimer's disease mice. SAS-0132 can be used in the research of neurocognitive disorders such as Alzheimer's disease.

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  • CAS. Nr.: 1644629-60-6
  • Formel: C24H29N3O2
  • Molecular Weight:391.51
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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