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Art. -Nr.: HY-401428

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TYK2 ligand 3

TYK2 ligand 3 is a TYK2 ligand that can be used for the synthesis of PROTACs, such as PROTAC TYK2 degrader-2 (HY-152227).

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CAS. Nr.: 2921556-43-4
Formel: C₂₃H₂₂N₈O₄
Molecular Weight:474.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

TYK2 ligand 3 Chemical Structure

CAS. Nr.: 2921556-43-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

TYK2 ligand 3 is a TYK2 ligand that can be used for the synthesis of PROTACs, such as PROTAC TYK2 degrader-2 (HY-152227)^[1].

IC₅₀ & Target

^[1]

Tyk2

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In Vitro

The ligand for the target protein causes the PROTAC to attach to the target protein, leading to its ubiquitination and subsequent degradation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS. Nr. 2921556-43-4
Molecular Weight 474.47
Formel C₂₃H₂₂N₈O₄
SMILES

CNC(C1=CN=C(C=C1NC2=C(C(C3=NN(C=N3)C)=CC=C2)OC)NC4=CC=C(C=N4)C(O)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Jun-Ya Kato, et al. Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor. Bioorg Med Chem Lett. 2023 Jan 1;79:129083. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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TYK2 ligand 3

Alle JAK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

TYK2 ligand 3 Related Classifications

HY-401428 Related Classifications

Bioz

Keywords

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