3',5'-UpU
3',5'-UpU (3',5'-Uridylyluridine) is a 3',5'-linked uridylyluridine dinucleotide. 3',5'-UpU undergoes cyclization/cleavage reactions to form uridine and uridine 2',3'-cyclic phosphate, and can also isomerize into 2',5'-UpU. Under the consecutive acid-base bifunctional catalysis of imidazole buffer, 3',5'-UpU undergoes cyclization/cleavage reactions via a phosphorane intermediate.
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- CAS. Nr.: 2415-43-2
- Formel: C18H23N4O14P
- Molecular Weight:550.37
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Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
Beschreibung
In Vitro
3',5'-UpU (3.2 mM; 80°C) undergoes cell-free cyclization/cleavage that is catalyzed 103-fold by a combination of 1 mM ZnCl2 and 10 mM imidazole at pH 7.00 and 80°C, with no acceleration of competing isomerization to 2',5'-UpU[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2415-43-2
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Appearance Solid
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Molecular Weight 550.37
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Formel C18H23N4O14P
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Color White to off-white
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](OP(OC[C@H]3O[C@@H](N(C(N4)=O)C=CC4=O)[C@H](O)[C@@H]3O)(O)=O)[C@@H](CO)O2)NC1=O
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Synonyms
3',5'-Uridylyluridine
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
3',5'-UpU Related Classifications
HY-159806 Related Classifications
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