Endothelin Receptor Control

Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na⁺/Cl^--potassium cotransporter inhibitor, with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl^-/NaCO^3- anion exchanger, promoting potassium and magnesium excretion while increasing calcium reabsorption. Xipamide is cleared primarily via the renal route and causes a transient decrease in glomerular filtration rate under specific conditions. Xipamide can be applied in research related to cardiovascular diseases, hypertension, advanced renal failure, and cirrhosis with ascites.

Xipamide-d₆ is the deuterated-labeled Xipamide (HY-W042301). Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na⁺/Cl^--potassium cotransporter inhibitor, with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl^-/NaCO^3- anion exchanger, promoting potassium and magnesium excretion while increasing calcium reabsorption. Xipamide is cleared primarily via the renal route and causes a transient decrease in glomerular filtration rate under specific conditions. Xipamide can be applied in research related to cardiovascular diseases, hypertension, advanced renal failure, and cirrhosis with ascites.

Xipamide (Standard) is the analytical standard of Xipamide (HY-W042301). This product is intended for research and analytical applications. Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na⁺/Cl^--potassium cotransporter inhibitor, with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl^-/NaCO^3- anion exchanger, promoting potassium and magnesium excretion while increasing calcium reabsorption. Xipamide is cleared primarily via the renal route and causes a transient decrease in glomerular filtration rate under specific conditions. Xipamide can be applied in research related to cardiovascular diseases, hypertension, advanced renal failure, and cirrhosis with ascites.