Beta-Asp-Arg
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Beta-Asp-Arg is a β-dipeptide and a product of cyanophycin degradation by cyanophycinase.
For research use only. We do not sell to patients.
- CAS No.: 2478-03-7
- Formula: C10H19N5O5
- Molecular Weight:289.29
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Beta-Asp-Arg serves as the substrate for Legionella longbeachae NSW150 dipeptidase Llo2535, whose hydrolysis of Beta-Asp-Arg supports the bacterium's nutrient utilization from cyanophycin[1].
Beta-Asp-Arg forms multiple hydrogen bond interactions with Synechocystis sp. PCC6803 cyanophycinase in a covalent co-complex structure[2].
Beta-Asp-Arg (200 μM) alone shows no measurable binding to inactive Synechocystis sp. PCC6803 cyanophycinase S132A, while the dimer (β-Asp-Arg)2 (300 μM) binds with high affinity (Kd = 9.3 μM) and the trimer (β-Asp-Arg)3 (200 μM) binds with lower affinity (Kd = 25.1 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2478-03-7
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Appearance Solid
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Molecular Weight 289.29
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Formula C10H19N5O5
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Sequence
βAsp-Arg
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Sequence Shortening
βAsp-R
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (345.67 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Cazalet C, et al. Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS genetics. 2010 Feb 19;6(2):e1000851. [Content Brief]
[2]. Sharon I, et al. The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochimica et biophysica acta. General subjects. 2022 Nov;1866(11):130217. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.4567 mL | 17.2837 mL | 34.5674 mL | 86.4185 mL |
| 5 mM | 0.6913 mL | 3.4567 mL | 6.9135 mL | 17.2837 mL | |
| 10 mM | 0.3457 mL | 1.7284 mL | 3.4567 mL | 8.6418 mL | |
| 15 mM | 0.2304 mL | 1.1522 mL | 2.3045 mL | 5.7612 mL | |
| 20 mM | 0.1728 mL | 0.8642 mL | 1.7284 mL | 4.3209 mL | |
| 25 mM | 0.1383 mL | 0.6913 mL | 1.3827 mL | 3.4567 mL | |
| 30 mM | 0.1152 mL | 0.5761 mL | 1.1522 mL | 2.8806 mL | |
| 40 mM | 0.0864 mL | 0.4321 mL | 0.8642 mL | 2.1605 mL | |
| 50 mM | 0.0691 mL | 0.3457 mL | 0.6913 mL | 1.7284 mL | |
| 60 mM | 0.0576 mL | 0.2881 mL | 0.5761 mL | 1.4403 mL | |
| 80 mM | 0.0432 mL | 0.2160 mL | 0.4321 mL | 1.0802 mL | |
| 100 mM | 0.0346 mL | 0.1728 mL | 0.3457 mL | 0.8642 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.