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Cat. No.: HY-108528

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BMS961

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BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity.

For research use only. We do not sell to patients.

Purity: 98.06%
CAS No.: 185629-22-5
Formula: C₂₃H₂₆FNO₄
Molecular Weight:399.46

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

BMS961 Chemical Structure

CAS No.: 185629-22-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Calculators
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Bioz

Biological Activity

Description

BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity^[1].

All RAR/RXR Isoforms :

In Vitro

BMS961 inhibits the expression of Dectin-1 and pro-inflammatory cytokines^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 185629-22-5
Appearance Solid
Molecular Weight 399.46
Formula C₂₃H₂₆FNO₄
Color White to off-white
SMILES

O=C(O)C1=CC=C(NC(C(O)C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)=O)C(F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang XC, et al. Effects of retinoic acid receptor-γ on the Aspergillus fumigatus induced innate immunity response in human corneal epithelial cells. Int J Ophthalmol. 2016 Dec 18;9(12):1713-1718. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
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Purity & Documentation
References

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BMS961

Differentiation Inducing Compound Library

Reprogramming Compound Library

Transcription Factor-Targeted Library

Nuclear Receptor Compound Library

Metabolic Enzyme Compound Library

Mitochondrial Toxicity Compound Library

Highly Selective Activators Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Immunology/Inflammation Compound Library

Metabolism/Protease Compound Library

All RAR/RXR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BMS961

Differentiation Inducing Compound Library

Reprogramming Compound Library

Transcription Factor-Targeted Library

Nuclear Receptor Compound Library

Metabolic Enzyme Compound Library

Mitochondrial Toxicity Compound Library

Highly Selective Activators Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Immunology/Inflammation Compound Library

Metabolism/Protease Compound Library

All RAR/RXR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BMS961 Related Classifications

HY-108528 Related Classifications