Grpr - gastrin releasing peptide receptor Gene

Also Known as GRP-R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14829

Summary

This gene encodes a multipass membrane protein that functions as a receptor for Gastrin releasing peptide. Signalling through this receptor is important in a variety of physiological processes, including responses to itching, satiety, and fear. [provided by RefSeq, May 2015]

Grpr Products (1)

mRNA Protein Name
NM_008177.3 NP_032203.1 gastrin-releasing peptide receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled peptide receptor activity IDA
IDA: Inferred from direct assay
1671171 MGI
enables neuropeptide receptor activity IMP
IMP: Inferred from mutant phenotype
26658875 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22000021 MGI
Biological Process GO Annotation Evidence References Source
involved in motor behavior IMP
IMP: Inferred from mutant phenotype
26658875 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26658875 MGI
involved in positive regulation of behavioral fear response IMP
IMP: Inferred from mutant phenotype
34610277 MGI
involved in positive regulation of respiratory gaseous exchange IMP
IMP: Inferred from mutant phenotype
26855425 MGI
involved in psychomotor behavior IMP
IMP: Inferred from mutant phenotype
28280205 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
11960700 MGI
involved in response to external biotic stimulus IMP
IMP: Inferred from mutant phenotype
28280205 MGI
involved in social behavior IMP
IMP: Inferred from mutant phenotype
28280205 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
1671171 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gastrin-releasing peptide receptor

  • GRP-preferring bombesin receptor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P0107 RC-3095 Antagonist 99.43% Phase 2
HY-P0039 BIM-26226 Antagonist 98.73% Phase 1

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-P0107A RC-3095 TFA Antagonist 99.66% Unkown
HY-W782083 p-SCN-Bn-NOTA trihydrochloride 99.75% Unkown
HY-N2909 Aurantiamide Inhibitor 99.56% Unkown
HY-P1423A BA 1 TFA Agonist 99.35% Unkown
HY-N2600 Kuwanon H 98.60% Unkown
HY-W343750 [Tyr4]-Bombesin Agonist 98.66% Unkown
HY-P10896 NOTA-P2-RM26 97.20% Unkown
HY-P5413 [Lys3]-Bombesin 99.39% Unkown
HY-115974 GRPR antagonist-1 99.80% Unkown
HY-115975 GRPR antagonist-2 Antagonist / Unkown
HY-176150 AMTG-DA1 Ligand / Unkown
HY-N2600R Kuwanon H (Standard) / Unkown
HY-P11352 JMV594 Antagonist / Unkown
HY-P11768 AMBA Ligand / Unkown
HY-P11769 RM2 Antagonist / Unkown
HY-P1423 BA 1 Agonist / Unkown
HY-P5520 GB-6 Chemical / Unkown
HY-RS05847 GRPR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-168633 PSMA/GRPR ligand 1 / Unkown
HY-180434 GRPR antagonist-3 Antagonist / Unkown
HY-RS17163 Grpr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23613 Grpr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grpr NCBI NCBI:2925