LL320
Based on 1 Customer Validation
LL320 is a selective NNMT inhibitor with a Ki,app of 6.8 nM. LL320 exhibits interactions with RNMT, DPH5, and SAHH.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 2672496-32-9
- Formula: C24H28N8O6
- Molecular Weight:524.53
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
NNMT[1]
Chemical Information
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CAS No. 2672496-32-9
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Appearance Solid
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Molecular Weight 524.53
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Formula C24H28N8O6
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Color White to off-white
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SMILES
O[C@@H]1[C@H](O)[C@@H](CN(CC#CC2=CC=CC(C(N)=O)=C2)CC[C@H](N)C(O)=O)O[C@H]1N3C(N=CN=C4N)=C4N=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (190.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9065 mL | 9.5323 mL | 19.0647 mL | 47.6617 mL |
| 5 mM | 0.3813 mL | 1.9065 mL | 3.8129 mL | 9.5323 mL | |
| 10 mM | 0.1906 mL | 0.9532 mL | 1.9065 mL | 4.7662 mL | |
| 15 mM | 0.1271 mL | 0.6355 mL | 1.2710 mL | 3.1774 mL | |
| 20 mM | 0.0953 mL | 0.4766 mL | 0.9532 mL | 2.3831 mL | |
| 25 mM | 0.0763 mL | 0.3813 mL | 0.7626 mL | 1.9065 mL | |
| 30 mM | 0.0635 mL | 0.3177 mL | 0.6355 mL | 1.5887 mL | |
| 40 mM | 0.0477 mL | 0.2383 mL | 0.4766 mL | 1.1915 mL | |
| 50 mM | 0.0381 mL | 0.1906 mL | 0.3813 mL | 0.9532 mL | |
| 60 mM | 0.0318 mL | 0.1589 mL | 0.3177 mL | 0.7944 mL | |
| 80 mM | 0.0238 mL | 0.1192 mL | 0.2383 mL | 0.5958 mL | |
| 100 mM | 0.0191 mL | 0.0953 mL | 0.1906 mL | 0.4766 mL |