m7GpppGmpG
m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%.
For research use only. We do not sell to patients.
- CAS No.: 1258049-00-1
- Formula: C32H43N15O25P4
- Molecular Weight:1161.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
RNA capping is a critical post-transcriptional modification step in eukaryotic mRNA, involving the addition of a 7-methylguanosine (m7G) cap structure to the 5' end of the mRNA. Catalyzed by the capping enzyme complex, this process is essential for mRNA stability, nuclear export, translation initiation, and immune evasion, and serves as a core element in research regarding mRNA vaccines and *in vitro* transcription technologies.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1258049-00-1
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Molecular Weight 1161.66
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Formula C32H43N15O25P4
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SMILES
O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](OC)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
m7GpppGmpG Related Classifications
HY-145977 Related Classifications
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