MCC-134
MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent.
For research use only. We do not sell to patients.
- CAS No.: 181238-67-5
- Formula: C16H17N3OS
- Molecular Weight:299.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 181238-67-5
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Molecular Weight 299.39
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Formula C16H17N3OS
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SMILES
S=C(NC)C1(CCC1)C(C2=CC=C(C=C2)N3C=CN=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. F Kolár, et al. MCC-134, a blocker of mitochondrial and opener of sarcolemmal ATP-sensitive K+ channels, abrogates cardioprotective effects of chronic hypoxia. Physiol Res. 2005;54(4):467-71. [Content Brief]
[2]. Norihito Sasaki, et al. MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning. Circulation. 2003 Mar 4;107(8):1183-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MCC-134 Related Classifications
HY-119306 Related Classifications
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