Diethylhomospermine
Based on 1 Customer Validation
Diethylhomospermine is a polyamine analogue. Diethylhomospermine has antitumor and antidiarrheal activity.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 119422-08-1
- Formula: C16H38N4
- Molecular Weight:286.50
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Storage:
RT, protect from light, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
0.2 μM
Compound: DEHSPM
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Inhibitory activity against growth of JURKAT cells after 144h.
Inhibitory activity against growth of JURKAT cells after 144h.
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[PMID: 9748365] |
| L1210 | IC50 |
0.05 μM
Compound: 20
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Growth inhibitory activity of compound on L1210 cells after 96 hours
Growth inhibitory activity of compound on L1210 cells after 96 hours
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[PMID: 8691443] |
| L1210 | IC50 |
0.07 μM
Compound: 11
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In vitro inhibition of L1210 growth after 96 hours.
In vitro inhibition of L1210 growth after 96 hours.
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[PMID: 7932575] |
| L1210 | IC50 |
0.07 μM
Compound: DEHSPM
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Growth uM after 96 hours
Growth uM after 96 hours
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[PMID: 10649978] |
| L1210 | IC50 |
0.07 μM
Compound: DEHSPM
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Inhibitory activity against growth of L1210 cells.
Inhibitory activity against growth of L1210 cells.
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[PMID: 9748365] |
| L1210 | IC50 |
0.2 μM
Compound: 11
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In vitro inhibition of L1210 growth after 48 hours.
In vitro inhibition of L1210 growth after 48 hours.
|
[PMID: 7932575] |
| L1210 | IC50 |
0.2 μM
Compound: 20
|
Growth inhibitory activity of compound on L1210 cells after 48 hours
Growth inhibitory activity of compound on L1210 cells after 48 hours
|
[PMID: 8691443] |
| L1210 | IC50 |
0.2 μM
Compound: DEHSPM
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Growth uM after 48 hours
Growth uM after 48 hours
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[PMID: 10649978] |
| Malme-3M | IC50 |
1 μM
Compound: 8, BEHSpm
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Antitumor activity against human MALME-3M cells
Antitumor activity against human MALME-3M cells
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[PMID: 19534534] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 119422-08-1
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Appearance Solid
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Molecular Weight 286.50
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Formula C16H38N4
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Color Off-white to light yellow
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SMILES
CCNCCCCNCCCCNCCCCNCC
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Synonyms
DEHSPM
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 1.43 mg/mL (4.99 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (262 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4904 mL | 17.4520 mL | 34.9040 mL | 87.2600 mL |
Diethylhomospermine Related Classifications
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