Diethylhomospermine
Based on 1 Customer Validation
Diethylhomospermine is a polyamine analogue. Diethylhomospermine has antitumor and antidiarrheal activity.
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- Pureté : 99.89%
- CAS No.: 119422-08-1
- Formule: C16H38N4
- Masse moléculaire:286.50
-
Stockage:
RT, protect from light, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
0.2 μM
Compound: DEHSPM
|
Inhibitory activity against growth of JURKAT cells after 144h.
Inhibitory activity against growth of JURKAT cells after 144h.
|
[PMID: 9748365] |
| L1210 | IC50 |
0.05 μM
Compound: 20
|
Growth inhibitory activity of compound on L1210 cells after 96 hours
Growth inhibitory activity of compound on L1210 cells after 96 hours
|
[PMID: 8691443] |
| L1210 | IC50 |
0.07 μM
Compound: 11
|
In vitro inhibition of L1210 growth after 96 hours.
In vitro inhibition of L1210 growth after 96 hours.
|
[PMID: 7932575] |
| L1210 | IC50 |
0.07 μM
Compound: DEHSPM
|
Growth uM after 96 hours
Growth uM after 96 hours
|
[PMID: 10649978] |
| L1210 | IC50 |
0.07 μM
Compound: DEHSPM
|
Inhibitory activity against growth of L1210 cells.
Inhibitory activity against growth of L1210 cells.
|
[PMID: 9748365] |
| L1210 | IC50 |
0.2 μM
Compound: 11
|
In vitro inhibition of L1210 growth after 48 hours.
In vitro inhibition of L1210 growth after 48 hours.
|
[PMID: 7932575] |
| L1210 | IC50 |
0.2 μM
Compound: 20
|
Growth inhibitory activity of compound on L1210 cells after 48 hours
Growth inhibitory activity of compound on L1210 cells after 48 hours
|
[PMID: 8691443] |
| L1210 | IC50 |
0.2 μM
Compound: DEHSPM
|
Growth uM after 48 hours
Growth uM after 48 hours
|
[PMID: 10649978] |
| Malme-3M | IC50 |
1 μM
Compound: 8, BEHSpm
|
Antitumor activity against human MALME-3M cells
Antitumor activity against human MALME-3M cells
|
[PMID: 19534534] |
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 119422-08-1
-
Appearance Solid
-
Masse moléculaire 286.50
-
Formule C16H38N4
-
Color Off-white to light yellow
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SMILES
CCNCCCCNCCCCNCCCCNCC
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Synonyms
DEHSPM
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
RT, protect from light, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvant et solubilité
In Vitro:
DMSO : 1.43 mg/mL (4.99 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (262 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4904 mL | 17.4520 mL | 34.9040 mL | 87.2600 mL |