Diglycolic acid
Based on 1 Customer Validation
Diglycolic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 98.35%
- CAS No.: 110-99-6
- Formula: C4H6O5
- Molecular Weight:134.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E599 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 110-99-6
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Appearance Solid
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Molecular Weight 134.09
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Formula C4H6O5
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Color White to off-white
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SMILES
O=C(O)COCC(=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (745.77 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4577 mL | 37.2884 mL | 74.5768 mL | 186.4419 mL |
| 5 mM | 1.4915 mL | 7.4577 mL | 14.9154 mL | 37.2884 mL | |
| 10 mM | 0.7458 mL | 3.7288 mL | 7.4577 mL | 18.6442 mL | |
| 15 mM | 0.4972 mL | 2.4859 mL | 4.9718 mL | 12.4295 mL | |
| 20 mM | 0.3729 mL | 1.8644 mL | 3.7288 mL | 9.3221 mL | |
| 25 mM | 0.2983 mL | 1.4915 mL | 2.9831 mL | 7.4577 mL | |
| 30 mM | 0.2486 mL | 1.2429 mL | 2.4859 mL | 6.2147 mL | |
| 40 mM | 0.1864 mL | 0.9322 mL | 1.8644 mL | 4.6610 mL | |
| 50 mM | 0.1492 mL | 0.7458 mL | 1.4915 mL | 3.7288 mL | |
| 60 mM | 0.1243 mL | 0.6215 mL | 1.2429 mL | 3.1074 mL | |
| 80 mM | 0.0932 mL | 0.4661 mL | 0.9322 mL | 2.3305 mL | |
| 100 mM | 0.0746 mL | 0.3729 mL | 0.7458 mL | 1.8644 mL |
Diglycolic acid Related Classifications
HY-W105832 Related Classifications
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