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United States

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製品番号: HY-N21732

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Dihydrocucurbitacin E

Dihydrocucurbitacin E is a cucurbitacin anticancer agent found in the rhizomes of Begonia nantoensis. Dihydrocucurbitacin E exhibits cytotoxic effects on gastric cancer cells and nasopharyngeal carcinoma cells. Dihydrocucurbitacin E can be used in research on gastric cancer and nasopharyngeal carcinoma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 28973-67-3
分子式: C₃₂H₄₆O₈
分子量:558.71

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dihydrocucurbitacin E 構造式

CAS 番号: 28973-67-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
NUGC-3	IC50	8.60 μg/mL	Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay.	14993759
HONE1 cell line	IC50	2.68 μg/mL	Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay.	14993759

体外実験

Anti-cancer

Dihydrocucurbitacin E (up to 20 μg/mL) is cytotoxic to human NUGC-3 gastric carcinoma and HONE-1 nasopharyngeal carcinoma cells, with IC₅₀ values of 8.60 μg/mL and 2.68 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

化学情報

CAS 番号 28973-67-3
分子量 558.71
分子式 C₃₂H₄₆O₈
SMILES

C[C@]12[C@@](C)([C@@]([C@@](C(CCC(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C1)[H])CC(=O)[C@]3(C)[C@]2(CC=C4[C@]3(C=C(O)C(=O)C4(C)C)[H])[H]
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Wu PL, et al. Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis. Chemical & pharmaceutical bulletin. 2004 Mar;52(3):345-9.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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