Diiodohydroxyquinoline (Standard)
Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas.
For research use only. We do not sell to patients.
- CAS No.: 83-73-8
- Formula: C₉H₅I₂NO
- Molecular Weight:396.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 83-73-8
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Molecular Weight 396.95
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Formula C₉H₅I₂NO
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SMILES
OC1=C2N=CC=CC2=C(I)C=C1I
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Synonyms
Iodoquinol (Standard); 5,7-Diiodo-8-hydroxyquinoline (Standard); 5,7-Diiodo-8-quinolinol (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Martínez-Castillo M, et al. Flavonoids as a Natural Treatment Against Entamoeba histolytica. Front Cell Infect Microbiol. 2018 Jun 22;8:209. [Content Brief]
[2]. Ghaskadbi S, et al. In vivo antimutagenic effect of ascorbic acid against mutagenicity of the common antiamebic drug diiodohydroxyquinoline[J]. Mutat Res. 1989 Mar;222(3):219-22. [Content Brief]
[3]. Yuan S, et al. Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system[J]. Pharmacol Res. 2020 Sep;159:104960. [Content Brief]
[5]. Cohlan SQ. Chronic nonspecific diarrhea in infants and children treated with diiodohydroxyquinoline. Pediatrics. 1956 Sep;18(3):424-32. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Diiodohydroxyquinoline (Standard) Related Classifications
HY-B1400R Related Classifications
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- Diiodohydroxyquinoline (Standard)
- 83-73-8
- Iodoquinol (Standard)
- 5,7-Diiodo-8-hydroxyquinoline (Standard)
- 5,7-Diiodo-8-quinolinol (Standard)
- Reference Standards
- Parasite
- SARS-CoV
- orally active
- antibacterial
- antiparasitic
- mutagenic potential
- anti-SARS-CoV-2 activity
- inflammationin
- testinal amebiasis
- amebic liver abscess
- Inhibitor
- inhibitor
- inhibit