Dimethenamid
Based on 1 Customer Validation
Dimethenamid is an acetamide herbicide that is widely used on soybeans and corns to inhibit weed growth. Dimethenamid not only lead to morphological abnormalities in zebrafish larvae but also reduces their viability. ROS production and inflammation responses were promoted in zebrafish larvae.
For research use only. We do not sell to patients.
- CAS No.: 87674-68-8
- Formula: C12H18ClNO2S
- Molecular Weight:275.79
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Bioactive Compound Library
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Apoptosis Compound Library
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Metabolism/Protease Compound Library
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Human Metabolite Library
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Cysteine Targeted Covalent Library
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Cysteine Targeted Covalent Fragment Library
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Cell Death Library
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MCE Bioactive Compound Library
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Pesticide Compound Library
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
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High-Throughput Bioactive Compound Library
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Biological Activity
Chemical Information
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CAS No. 87674-68-8
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Appearance Oil
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Molecular Weight 275.79
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Formula C12H18ClNO2S
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SMILES
O=C(CCl)N(C(COC)C)C1=C(C)SC=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (362.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.06 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.06 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6259 mL | 18.1297 mL | 36.2595 mL | 90.6487 mL |
| 5 mM | 0.7252 mL | 3.6259 mL | 7.2519 mL | 18.1297 mL | |
| 10 mM | 0.3626 mL | 1.8130 mL | 3.6259 mL | 9.0649 mL | |
| 15 mM | 0.2417 mL | 1.2086 mL | 2.4173 mL | 6.0432 mL | |
| 20 mM | 0.1813 mL | 0.9065 mL | 1.8130 mL | 4.5324 mL | |
| 25 mM | 0.1450 mL | 0.7252 mL | 1.4504 mL | 3.6259 mL | |
| 30 mM | 0.1209 mL | 0.6043 mL | 1.2086 mL | 3.0216 mL | |
| 40 mM | 0.0906 mL | 0.4532 mL | 0.9065 mL | 2.2662 mL | |
| 50 mM | 0.0725 mL | 0.3626 mL | 0.7252 mL | 1.8130 mL | |
| 60 mM | 0.0604 mL | 0.3022 mL | 0.6043 mL | 1.5108 mL | |
| 80 mM | 0.0453 mL | 0.2266 mL | 0.4532 mL | 1.1331 mL | |
| 100 mM | 0.0363 mL | 0.1813 mL | 0.3626 mL | 0.9065 mL |
Dimethenamid Related Classifications
HY-124889 Related Classifications
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