1,8-Octanedithiol
Based on 1 Customer Validation
1,8-Octanedithiol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.00%
- CAS No.: 1191-62-4
- Formula: C8H18S2
- Molecular Weight:178.35
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E94 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1191-62-4
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Appearance Liquid
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Molecular Weight 178.35
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Formula C8H18S2
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Color Colorless to light yellow
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SMILES
SCCCCCCCCS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (560.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6070 mL | 28.0348 mL | 56.0695 mL | 140.1738 mL |
| 5 mM | 1.1214 mL | 5.6070 mL | 11.2139 mL | 28.0348 mL | |
| 10 mM | 0.5607 mL | 2.8035 mL | 5.6070 mL | 14.0174 mL | |
| 15 mM | 0.3738 mL | 1.8690 mL | 3.7380 mL | 9.3449 mL | |
| 20 mM | 0.2803 mL | 1.4017 mL | 2.8035 mL | 7.0087 mL | |
| 25 mM | 0.2243 mL | 1.1214 mL | 2.2428 mL | 5.6070 mL | |
| 30 mM | 0.1869 mL | 0.9345 mL | 1.8690 mL | 4.6725 mL | |
| 40 mM | 0.1402 mL | 0.7009 mL | 1.4017 mL | 3.5043 mL | |
| 50 mM | 0.1121 mL | 0.5607 mL | 1.1214 mL | 2.8035 mL | |
| 60 mM | 0.0934 mL | 0.4672 mL | 0.9345 mL | 2.3362 mL | |
| 80 mM | 0.0701 mL | 0.3504 mL | 0.7009 mL | 1.7522 mL | |
| 100 mM | 0.0561 mL | 0.2803 mL | 0.5607 mL | 1.4017 mL |
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